1Health Claims der EFSA im Bezug zu Vitamin C und B1: Vitamin C trägt zu einer normalen Kollagenbildung für eine normale Funktion der Blutgefäßen bei und schützt die Zellen vor oxidativem Stress. Vitamin B1 trägt zu einer normalen Herzfunktion bei.
2Mc Namara K, Alzubaidi H, Jackson JK. Cardiovascular disease as a leading cause of death: how are pharmacists getting involved? Integr Pharm Res Pract. 2019 Feb 4;8:1-11. doi: 10.2147/IPRP.S133088. PMID: 30788283; PMCID: PMC6366352.
3Roth GA, Mensah GA, Johnson CO, Addolorato G, Ammirati E, Baddour LM, Barengo NC, et. al. GBD-NHLBI-JACC Global Burden of Cardiovascular Diseases Writing Group. Global Burden of Cardiovascular Diseases and Risk Factors, 1990-2019: Update From the GBD 2019 Study. J Am Coll Cardiol. 2020 Dec 22;76(25):2982-3021. doi: 10.1016/j.jacc.2020.11.010. Erratum in: J Am Coll Cardiol. 2021 Apr 20;77(15):1958-1959. PMID: 33309175; PMCID: PMC7755038.
4Gaziano T, Reddy KS, Paccaud F, et al. Cardiovascular Disease. In: Jamison DT, Breman JG, Measham AR, et al., editors. Disease Control Priorities in Developing Countries. 2nd edition. Washington (DC): The International Bank for Reconstruction and Development / The World Bank; 2006. Chapter 33. Available from: https://www.ncbi.nlm.nih.gov/books/NBK11767/ Co-published by Oxford University Press, New York.
5Minelli P, Montinari MR. The Mediterranean Diet And Cardioprotection: Historical Overview And Current Research. J Multidiscip Healthc. 2019 Sep 27;12:805-815. doi: 10.2147/JMDH.S219875. PMID: 31632049; PMCID: PMC6776290.
6Pinckard K, Baskin KK, Stanford KI. Effects of Exercise to Improve Cardiovascular Health. Front Cardiovasc Med. 2019 Jun 4;6:69. doi: 10.3389/fcvm.2019.00069. PMID: 31214598; PMCID: PMC6557987.
7Kostner KM, Kostner GM. Lp(a) and the Risk for Cardiovascular Disease: Focus on the Lp(a) Paradox in Diabetes Mellitus. Int J Mol Sci. 2022 Mar 25;23(7):3584. doi: 10.3390/ijms23073584. PMID: 35408941; PMCID: PMC8998850.
8Leon BM, Maddox TM. Diabetes and cardiovascular disease: Epidemiology, biological mechanisms, treatment recommendations and future research. World J Diabetes. 2015 Oct 10;6(13):1246-58. doi: 10.4239/wjd.v6.i13.1246. PMID: 26468341; PMCID: PMC4600176.
9Martín-Timón I, Sevillano-Collantes C, Segura-Galindo A, Del Cañizo-Gómez FJ. Type 2 diabetes and cardiovascular disease: Have all risk factors the same strength? World J Diabetes. 2014 Aug 15;5(4):444-70. doi: 10.4239/wjd.v5.i4.444. PMID: 25126392; PMCID: PMC4127581.
10Xu C, Mathews AE, Rodrigues C, Eudy BJ, Rowe CA, O’Donoughue A, Percival SS. Aged garlic extract supplementation modifies inflammation and immunity of adults with obesity: A randomized, double-blind, placebo-controlled clinical trial. Clin Nutr ESPEN. 2018 Apr;24:148-155. doi: 10.1016/j.clnesp.2017.11.010. Epub 2018 Jan 3. PMID: 29576354.
11Gruenwald J, Bongartz U, Bothe G, Uebelhack R. Effects of aged garlic extract on arterial elasticity in a placebo-controlled clinical trial using EndoPAT™ technology. Exp Ther Med. 2020 Feb;19(2):1490-1499. doi: 10.3892/etm.2019.8378. Epub 2019 Dec 27. PMID: 32010328; PMCID: PMC6966200.
12Valls RM, Companys J, Calderón-Pérez L, Salamanca P, Pla-Pagà L, Sandoval-Ramírez BA, Bueno A, Puzo J, Crescenti A, Bas JMD, Caimari A, Salamanca A, Espinel AE, Pedret A, Arola L, Solà R. Effects of an Optimized Aged Garlic Extract on Cardiovascular Disease Risk Factors in Moderate Hypercholesterolemic Subjects: A Randomized, Crossover, Double-Blind, Sustainedand Controlled Study. Nutrients. 2022 Jan 18;14(3):405. doi: 10.3390/nu14030405. PMID: 35276764; PMCID: PMC8838962.
13Wlosinska M, Nilsson AC, Hlebowicz J, Fakhro M, Malmsjö M, Lindstedt S. Aged Garlic Extract Reduces IL-6: A Double-Blind Placebo-Controlled Trial in Females with a Low Risk of Cardiovascular Disease. Evid Based Complement Alternat Med. 2021 Mar 31;2021:6636875. doi: 10.1155/2021/6636875. PMID: 33868439; PMCID: PMC8032523.
14Redwood E, Lam V, Takechi R, Kerr DA, Jackaman C, Sharif A, Mamo JCL. Aged garlic extract as a potential prophylactic to reduce the progression of endometriosis and associated pain burden. Front Pain Res (Lausanne). 2022 Nov 17;3:1057830. doi: 10.3389/fpain.2022.1057830. PMID: 36466216; PMCID: PMC9714464.
15Ried K. Garlic lowers blood pressure in hypertensive subjects, improves arterial stiffness and gut microbiota: A review and meta-analysis. Exp Ther Med. 2020 Feb;19(2):1472-1478. doi: 10.3892/etm.2019.8374. Epub 2019 Dec 27. PMID: 32010325; PMCID: PMC6966103.
16Elosta A, Slevin M, Rahman K, Ahmed N. Aged garlic has more potent antiglycation and antioxidant properties compared to fresh garlic extract in vitro. Sci Rep. 2017 Jan 4;7:39613. doi: 10.1038/srep39613. PMID: 28051097; PMCID: PMC5209668.
17Ray B, Chauhan NB, Lahiri DK. The “aged garlic extract:” (AGE) and one of its active ingredients S-allyl-L-cysteine (SAC) as potential preventive and therapeutic agents for Alzheimer’s disease (AD). Curr Med Chem. 2011;18(22):3306-13. doi: 10.2174/092986711796504664. PMID: 21728972; PMCID: PMC3941700.
19Zugelassener Health Claim zu Olivenöl-Polyphenolen: „Olivenöl-Polyphenole tragen dazu bei, die Blutfette vor oxidativem Stress zu schützen.“
18Mazzocchi A, Leone L, Agostoni C, Pali-Schöll I. The Secrets of the Mediterranean Diet. Does [Only] Olive Oil Matter? Nutrients. 2019 Dec 3;11(12):2941. doi: 10.3390/nu11122941. PMID: 31817038; PMCID: PMC6949890.
19Zugelassener Health Claim zu Olivenöl-Polyphenolen: „Olivenöl-Polyphenole tragen dazu bei, die Blutfette vor oxidativem Stress zu schützen.“
20Omar SH. Oleuropein in olive and its pharmacological effects. Sci Pharm. 2010 Apr-Jun;78(2):133-54. doi: 10.3797/scipharm.0912-18. Epub 2010 Apr 23. PMID: 21179340; PMCID: PMC3002804.
21Romani A et al. Health effects of phenolic compounds found in extra-virgine olive oil, by-products, and leaf of Olea europaea L. Nutrients 2019;11:1776
22Razmpoosh E, Abdollahi S, Mousavirad M, Clark CCT, Soltani S. The effects of olive leaf extract on cardiovascular risk factors in the general adult population: a systematic review and meta-analysis of randomized controlled trials. Diabetol Metab Syndr. 2022 Oct 21;14(1):151. doi: 10.1186/s13098-022-00920-y. PMID: 36271405; PMCID: PMC9585795.
23González-Hedström D, García-Villalón ÁL, Amor S, de la Fuente-Fernández M, Almodóvar P, Prodanov M, Priego T, Martín AI, Inarejos-García AM, Granado M. Olive leaf extract supplementation improves the vascular and metabolic alterations associated with aging in Wistar rats. Sci Rep. 2021 Apr 14;11(1):8188. doi: 10.1038/s41598-021-87628-7. PMID: 33854149; PMCID: PMC8046982.
24Haidari F, Shayesteh F, Mohammad-Shahi M, Jalali MT, Ahmadi-Angali K. Olive Leaf Extract Supplementation Combined with Calorie-Restricted Diet on Reducing Body Weight and Fat Mass in Obese Women: Result of a Randomized Control Trial. Clin Nutr Res. 2021 Oct 31;10(4):314-329. doi: 10.7762/cnr.2021.10.4.314. PMID: 34796136; PMCID: PMC8575641.